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5K4W

Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NADH and L-threonine refined to 1.72 angstroms

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, C)
L-threonine 3-dehydrogenasepolymer32135847.32UniProt (Q7YW97)
Pfam (PF01370)
Trypanosoma brucei
2C, G
(A, C)
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDEnon-polymer665.42Chemie (NAI)
3D, H
(A, C)
THREONINEnon-polymer119.12Chemie (THR)
4E, I, J
(A, C)
GLYCEROLnon-polymer92.13Chemie (GOL)
5F, K
(A, C)
SODIUM IONnon-polymer23.02Chemie (NA)
6L, M
(A, C)
waterwater18.0420Chemie (HOH)
Sequence modifications
A, C: 1003 - 1321 (UniProt: Q7YW97)
PDBExternal DatabaseDetails
His 1001-expression tag
Met 1002-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight71694.6
Non-Polymers*Number of molecules9
Total formula weight1891.4
All*Total formula weight73586.0
*Water molecules are not included.

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PDB entries from 2025-11-05

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