5K14
HIV-1 Reverse Transcriptase in complex with a 2,6-difluorophenyl DAPY analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HIV-1 reverse transcriptase(isolate HXB2) | polymer | 560 | 64562.9 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) | |
| 2 | B | HIV-1 reverse transcriptase (isolate LW123) | polymer | 440 | 51399.0 | 1 | UniProt (P0C6F2) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1) | |
| 3 | A | 4-{[4-(2,6-difluoro-4-methoxybenzene-1-carbonyl)pyrimidin-2-yl]amino}benzonitrile | non-polymer | 366.3 | 1 | Chemie (IB1) | |||
| 4 | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
B: 1 - 440 (UniProt: P0C6F2)
| PDB | External Database | Details |
|---|---|---|
| Ala 360 | Thr 947 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115962.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 366.3 | |
| All* | Total formula weight | 116328.3 |
