5JZX

Crystal Structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	UDP-N-acetylenolpyruvoylglucosamine reductase	polymer	405	42395.1	6	UniProt (P9WJL9) Pfam (PF01565) Pfam (PF02873)	Mycobacterium tuberculosis H37Rv	UDP-N-acetylmuramate dehydrogenase
2	G, I, K, M, N... (A, B, C, D, E...)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	6	Chemie (FAD)
3	H, J, L (A, B, C)	POTASSIUM ION	non-polymer		39.1	3	Chemie (K)
4	P, Q, R, S, T... (A, B, C, D, E...)	water	water		18.0	363	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 369 (UniProt: P9WJL9)

PDB	External Database	Details
Met -35	-	expression tag
Gly -34	-	expression tag
Ser -33	-	expression tag
Ser -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
Ser -25	-	expression tag
Ser -24	-	expression tag
Gly -23	-	expression tag
Leu -22	-	expression tag
Val -21	-	expression tag
Pro -20	-	expression tag
Arg -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
Met -15	-	expression tag
Ala -14	-	expression tag
Ser -13	-	expression tag
Met -12	-	expression tag
Thr -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Gln -8	-	expression tag
Gln -7	-	expression tag
Met -6	-	expression tag
Gly -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	254370.6
Non-Polymers*	Number of molecules	9
	Total formula weight	4830.6
All*	Total formula weight	259201.2

*Water molecules are not included.