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5JXW

2.25 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Neplanocin-A and NAD

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Adenosylhomocysteinasepolymer49856200.74UniProt (Q5CPH1)
Pfam (PF05221)
Pfam (PF00670)
Cryptosporidium parvum
2E, I, N, Q
(A, B, C, D)
Neplanocin-Anon-polymer263.34Chemie (6OS)
3F, J, O, R
(A, B, C, D)
NICOTINAMIDE-ADENINE-DINUCLEOTIDEnon-polymer663.44Chemie (NAD)
4G, H, M, U
(A, B, D)
GLYCEROLnon-polymer92.14Chemie (GOL)
5K, S
(B, D)
HEXAETHYLENE GLYCOLnon-polymer282.32Chemie (P6G)
6L, P, T
(B, C, D)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.13Chemie (TRS)
7V, W, X, Y
(A, B, C, D)
waterwater18.0754Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 495 (UniProt: Q5CPH1)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight224802.7
Non-Polymers*Number of molecules17
Total formula weight5006.2
All*Total formula weight229808.9
*Water molecules are not included.

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PDB entries from 2025-07-23

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