5JXW
2.25 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Neplanocin-A and NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Adenosylhomocysteinase | polymer | 498 | 56200.7 | 4 | UniProt (Q5CPH1) Pfam (PF05221) Pfam (PF00670) | Cryptosporidium parvum | |
| 2 | E, I, N, Q (A, B, C, D) | Neplanocin-A | non-polymer | 263.3 | 4 | Chemie (6OS) PubChem (72968) PubChem (330164) PubChem (490421) PubChem (506143) PubChem (13118243) PubChem (18634555) PubChem (44291239) PubChem (44351967) PubChem (92262655) PubChem (11242487) PubChem (58492817) PubChem (59963007) | |||
| 3 | F, J, O, R (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 4 | G, H, M, U (A, B, D) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 5 | K, S (B, D) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 2 | Chemie (P6G) PubChem (17472) | |||
| 6 | L, P, T (B, C, D) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 3 | Chemie (TRS) PubChem (3777159) | |||
| 7 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 754 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 495 (UniProt: Q5CPH1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 224802.7 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 5006.2 | |
| All* | Total formula weight | 229808.9 |
