5JXJ
Structure of the proprotein convertase furin complexed to meta-guanidinomethyl-Phac-RVR-Amba in presence of EDTA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Furin | polymer | 482 | 52388.6 | 1 | UniProt (P09958) Pfam (PF00082) Pfam (PF01483) | Homo sapiens (Human) | Dibasic-processing enzyme,Paired basic amino acid residue-cleaving enzyme,PACE |
| 2 | B (H) | 2UC-ARG-VAL-ARG-00S | polymer | 5 | 751.9 | 1 | BIRD (PRD_001220) | synthetic construct | |
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D, E, F, G, H... (A) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 5 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | K, L (A, H) | water | water | 18.0 | 460 | Chemie (HOH) |
Sequence modifications
A: 108 - 574 (UniProt: P09958)
| PDB | External Database | Details |
|---|---|---|
| Ser 575 | - | expression tag |
| Gly 576 | - | expression tag |
| Ser 577 | - | expression tag |
| Leu 578 | - | expression tag |
| Val 579 | - | expression tag |
| Pro 580 | - | expression tag |
| Arg 581 | - | expression tag |
| Gly 582 | - | expression tag |
| Ser 583 | - | expression tag |
| His 584 | - | expression tag |
| His 585 | - | expression tag |
| His 586 | - | expression tag |
| His 587 | - | expression tag |
| His 588 | - | expression tag |
| His 589 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53140.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 213.5 | |
| All* | Total formula weight | 53354.0 |
