5JW9

The Crystal Structure of ELL2 Oclludin Domain and AFF4 peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	AF4/FMR2 family member 4	polymer	64	6629.0	1	UniProt (Q9UHB7) In PDB	Homo sapiens (Human)	ALL1-fused gene from chromosome 5q31 protein,Protein AF-5q31,Major CDK9 elongation factor-associated protein
2	B	RNA polymerase II elongation factor ELL2	polymer	122	14923.3	1	UniProt (O00472) Pfam (PF07303) In PDB	Homo sapiens (Human)
3		water	water		18.0	97	Chemie (HOH)

Sequence modifications

A: 1 - 51 (UniProt: Q9UHB7)

PDB	External Database	Details
Gly -4	-	expression tag
Ala -3	-	expression tag
Mse -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Gly 52	-	expression tag
Ser 53	-	expression tag
Gly 54	-	expression tag
Ser 55	-	expression tag
Gly 56	-	expression tag
Ser 57	-	expression tag
Gly 58	-	expression tag
Ser 59	-	expression tag

B: 519 - 640 (UniProt: O00472)

PDB	External Database	Details
Mse 627	Leu 627	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21552.4
All*	Total formula weight	21552.4

*Water molecules are not included.