5JVT
Crystal structure of the DNA binding domain of transcription factor FLI1 in complex with an 11-mer DNA GACCGGAAGTG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, D, G) | Friend leukemia integration 1 transcription factor | polymer | 104 | 12098.7 | 3 | UniProt (Q01543) Pfam (PF00178) | Homo sapiens (Human) | Proto-oncogene Fli-1,Transcription factor ERGB |
| 2 | B, E, H (B, E, H) | DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3') | polymer | 11 | 3423.2 | 3 | Endothia gyrosa | ||
| 3 | C, F, I (C, F, I) | DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3') | polymer | 11 | 3285.1 | 3 | Endothia gyrosa | ||
| 4 | J (D) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | K (G) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | L, M (B, D) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A, D, G: 276 - 375 (UniProt: Q01543)
| PDB | External Database | Details |
|---|---|---|
| Gly 272 | - | expression tag |
| Pro 273 | - | expression tag |
| His 274 | - | expression tag |
| Met 275 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 56421.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 187.1 | |
| All* | Total formula weight | 56608.2 |
