5JU8
Cryo-EM structure of an ErmBL-stalled ribosome in complex with P-, and E-tRNA
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AA) | 16S ribosomal RNA | polymer | 1539 | 498725.4 | 1 | GenBank (731469900) | Escherichia coli K-12 | |
| 2 | B (AB) | 30S ribosomal protein S2 | polymer | 240 | 26652.6 | 1 | UniProt (P0A7V0) Pfam (PF00318) | Escherichia coli (strain K12) | |
| 3 | C (AC) | 30S ribosomal protein S3 | polymer | 233 | 26031.3 | 1 | UniProt (P0A7V3) Pfam (PF07650) Pfam (PF00189) | Escherichia coli (strain K12) | |
| 4 | D (AD) | 30S ribosomal protein S4 | polymer | 206 | 23514.2 | 1 | UniProt (P0A7V8) Pfam (PF00163) Pfam (PF01479) | Escherichia coli (strain K12) | |
| 5 | E (AE) | 30S ribosomal protein S5 | polymer | 167 | 17629.4 | 1 | UniProt (P0A7W1) Pfam (PF00333) Pfam (PF03719) | Escherichia coli (strain K12) | |
| 6 | F (AF) | 30S ribosomal protein S6 | polymer | 135 | 15727.5 | 1 | UniProt (P02358) Pfam (PF01250) | Escherichia coli (strain K12) | |
| 7 | G (AG) | 30S ribosomal protein S7 | polymer | 179 | 20055.2 | 1 | UniProt (P02359) Pfam (PF00177) | Escherichia coli (strain K12) | |
| 8 | H (AH) | 30S ribosomal protein S8 | polymer | 130 | 14146.6 | 1 | UniProt (P0A7W7) Pfam (PF00410) | Escherichia coli (strain K12) | |
| 9 | I (AI) | 30S ribosomal protein S9 | polymer | 130 | 14886.3 | 1 | UniProt (P0A7X3) Pfam (PF00380) | Escherichia coli (strain K12) | |
| 10 | J (AJ) | 30S ribosomal protein S10 | polymer | 103 | 11755.6 | 1 | UniProt (P0A7R5) Pfam (PF00338) | Escherichia coli (strain K12) | |
| 11 | K (AK) | 30S ribosomal protein S11 | polymer | 129 | 13871.0 | 1 | UniProt (P0A7R9) Pfam (PF00411) | Escherichia coli (strain K12) | |
| 12 | L (AL) | 30S ribosomal protein S12 | polymer | 124 | 13768.2 | 1 | UniProt (P0A7S3) Pfam (PF00164) | Escherichia coli (strain K12) | |
| 13 | M (AM) | 30S ribosomal protein S13 | polymer | 118 | 13128.5 | 1 | UniProt (P0A7S9) Pfam (PF00416) | Escherichia coli (strain K12) | |
| 14 | N (AN) | 30S ribosomal protein S14 | polymer | 102 | 11677.6 | 1 | UniProt (P0AG59) Pfam (PF00253) | Escherichia coli (strain K12) | |
| 15 | O (AO) | 30S ribosomal protein S15 | polymer | 89 | 10290.8 | 1 | UniProt (P0ADZ4) Pfam (PF00312) | Escherichia coli (strain K12) | |
| 16 | P (AP) | 30S ribosomal protein S16 | polymer | 82 | 9207.6 | 1 | UniProt (P0A7T3) Pfam (PF00886) | Escherichia coli (strain K12) | |
| 17 | Q (AQ) | 30S ribosomal protein S17 | polymer | 84 | 9724.5 | 1 | UniProt (P0AG63) Pfam (PF00366) | Escherichia coli (strain K12) | |
| 18 | R (AR) | 30S ribosomal protein S18 | polymer | 75 | 9005.5 | 1 | UniProt (P0A7T7) Pfam (PF01084) | Escherichia coli (strain K12) | |
| 19 | S (AS) | 30S ribosomal protein S19 | polymer | 92 | 10455.4 | 1 | UniProt (P0A7U3) Pfam (PF00203) | Escherichia coli (strain K12) | |
| 20 | T (AT) | 30S ribosomal protein S20 | polymer | 87 | 9708.5 | 1 | UniProt (P0A7U7) Pfam (PF01649) | Escherichia coli (strain K12) | |
| 21 | U (AU) | 30S ribosomal protein S21 | polymer | 71 | 8524.0 | 1 | UniProt (P68679) Pfam (PF01165) | Escherichia coli (strain K12) | |
| 22 | V (AV) | mRNA | polymer | 10 | 3233.0 | 1 | Escherichia coli | ||
| 23 | W (AX) | P-site tRNA Aspartate | polymer | 77 | 25010.1 | 1 | Escherichia coli (strain K12) | ||
| 24 | X (AY) | E-site tRNA Valine | polymer | 71 | 23066.9 | 1 | Escherichia coli (strain K12) | ||
| 25 | Y (BA) | 23S ribosomal RNA | polymer | 2903 | 941306.2 | 1 | GenBank (802133627) | Escherichia coli (strain K12) | |
| 26 | Z (BB) | 5S ribosomal RNA | polymer | 120 | 38813.1 | 1 | GenBank (991970073) | Escherichia coli (strain K12) | |
| 27 | AA (BC) | 50S ribosomal protein L2 | polymer | 273 | 29923.6 | 1 | UniProt (P60422) Pfam (PF00181) Pfam (PF03947) | Escherichia coli (strain K12) | |
| 28 | BA (BD) | 50S ribosomal protein L3 | polymer | 209 | 22277.5 | 1 | UniProt (P60438) Pfam (PF00297) | Escherichia coli (strain K12) | |
| 29 | CA (BE) | 50S ribosomal protein L4 | polymer | 201 | 22121.6 | 1 | UniProt (P60723) Pfam (PF00573) | Escherichia coli (strain K12) | |
| 30 | DA (BF) | 50S ribosomal protein L5 | polymer | 179 | 20333.6 | 1 | UniProt (P62399) Pfam (PF00281) Pfam (PF00673) | Escherichia coli (strain K12) | |
| 31 | EA (BG) | 50S ribosomal protein L6 | polymer | 177 | 18932.8 | 1 | UniProt (P0AG55) Pfam (PF00347) | Escherichia coli (strain K12) | |
| 32 | FA (BH) | 50S ribosomal protein L9 | polymer | 149 | 15789.0 | 1 | UniProt (P0A7R1) Pfam (PF01281) Pfam (PF03948) | Escherichia coli (strain K12) | |
| 33 | GA (BI) | 50S ribosomal protein L11 | polymer | 142 | 14894.4 | 1 | UniProt (P0A7J7) Pfam (PF03946) Pfam (PF00298) | Escherichia coli (strain K12) | |
| 34 | HA (BJ) | 50S ribosomal protein L13 | polymer | 142 | 16050.6 | 1 | UniProt (P0AA10) Pfam (PF00572) | Escherichia coli (strain K12) | |
| 35 | IA (BK) | 50S ribosomal protein L14 | polymer | 123 | 13565.1 | 1 | UniProt (P0ADY3) Pfam (PF00238) | Escherichia coli (strain K12) | |
| 36 | JA (BL) | 50S ribosomal protein L15 | polymer | 144 | 15008.5 | 1 | UniProt (P02413) Pfam (PF00828) | Escherichia coli (strain K12) | |
| 37 | KA (BM) | 50S ribosomal protein L16 | polymer | 136 | 15312.3 | 1 | UniProt (P0ADY7) Pfam (PF00252) | Escherichia coli (strain K12) | |
| 38 | LA (BN) | 50S ribosomal protein L17 | polymer | 127 | 14393.7 | 1 | UniProt (P0AG44) Pfam (PF01196) | Escherichia coli (strain K12) | |
| 39 | MA (BO) | 50S ribosomal protein L18 | polymer | 117 | 12794.7 | 1 | UniProt (P0C018) Pfam (PF00861) | Escherichia coli (strain K12) | |
| 40 | NA (BP) | 50S ribosomal protein L19 | polymer | 115 | 13159.3 | 1 | UniProt (P0A7K6) Pfam (PF01245) | Escherichia coli (strain K12) | |
| 41 | OA (BQ) | 50S ribosomal protein L20 | polymer | 118 | 13528.0 | 1 | UniProt (P0A7L3) Pfam (PF00453) | Escherichia coli (strain K12) | |
| 42 | PA (BR) | 50S ribosomal protein L21 | polymer | 103 | 11586.4 | 1 | UniProt (P0AG48) Pfam (PF00829) | Escherichia coli (strain K12) | |
| 43 | QA (BS) | 50S ribosomal protein L22 | polymer | 110 | 12253.4 | 1 | UniProt (P61175) Pfam (PF00237) | Escherichia coli (strain K12) | |
| 44 | RA (BT) | 50S ribosomal protein L23 | polymer | 100 | 11222.2 | 1 | UniProt (P0ADZ0) Pfam (PF00276) | Escherichia coli (strain K12) | |
| 45 | SA (BU) | 50S ribosomal protein L24 | polymer | 104 | 11339.3 | 1 | UniProt (P60624) Pfam (PF00467) Pfam (PF17136) | Escherichia coli (strain K12) | |
| 46 | TA (BV) | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 1 | UniProt (P68919) Pfam (PF01386) | Escherichia coli (strain K12) | |
| 47 | UA (BW) | 50S ribosomal protein L27 | polymer | 85 | 9146.5 | 1 | UniProt (P0A7L8) Pfam (PF01016) | Escherichia coli (strain K12) | |
| 48 | VA (BX) | 50S ribosomal protein L28 | polymer | 78 | 9027.6 | 1 | UniProt (P0A7M2) Pfam (PF00830) | Escherichia coli (strain K12) | |
| 49 | WA (BY) | 50S ribosomal protein L29 | polymer | 63 | 7286.5 | 1 | UniProt (P0A7M6) Pfam (PF00831) | Escherichia coli (strain K12) | |
| 50 | XA (BZ) | 50S ribosomal protein L30 | polymer | 59 | 6554.8 | 1 | UniProt (P0AG51) Pfam (PF00327) | Escherichia coli (strain K12) | |
| 51 | YA (B0) | 50S ribosomal protein L32 | polymer | 57 | 6463.4 | 1 | UniProt (P0A7N4) Pfam (PF01783) | Escherichia coli (strain K12) | |
| 52 | ZA (B1) | 50S ribosomal protein L33 | polymer | 55 | 6388.6 | 1 | UniProt (P0A7N9) Pfam (PF00471) | Escherichia coli (strain K12) | |
| 53 | AB (B2) | 50S ribosomal protein L34 | polymer | 46 | 5397.5 | 1 | UniProt (P0A7P5) Pfam (PF00468) | Escherichia coli (strain K12) | |
| 54 | BB (B3) | 50S ribosomal protein L35 | polymer | 65 | 7313.0 | 1 | UniProt (P0A7Q1) Pfam (PF01632) | Escherichia coli (strain K12) | Ribosomal protein A |
| 55 | CB (B4) | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 1 | UniProt (P0A7Q6) Pfam (PF00444) | Escherichia coli (strain K12) | Ribosomal protein B |
| 56 | DB (B5) | ErmBL | polymer | 9 | 1080.2 | 1 | Escherichia coli | ||
| 57 | EB (BA) | ERYTHROMYCIN A | non-polymer | 733.9 | 1 | Chemie (ERY) PubChem (16219331) PubChem (16757675) PubChem (22489166) PubChem (22836457) PubChem (22836628) PubChem (23229191) PubChem (24797108) PubChem (12560) PubChem (16219337) PubChem (16401342) PubChem (16759276) PubChem (18397931) PubChem (44451949) PubChem (18528813) PubChem (21550772) PubChem (22836626) PubChem (45107170) PubChem (45107190) PubChem (45107269) PubChem (45107273) PubChem (49867933) PubChem (51066560) PubChem (53384904) PubChem (53384913) PubChem (57358551) PubChem (44317775) PubChem (57587180) PubChem (44547821) PubChem (44563509) PubChem (45107581) PubChem (59974395) PubChem (60044171) PubChem (60086513) PubChem (66577477) PubChem (71024089) PubChem (50987679) PubChem (53393685) PubChem (54359201) PubChem (57357418) PubChem (57893297) PubChem (58594795) PubChem (58593559) PubChem (59022390) PubChem (59062422) PubChem (59064284) PubChem (59093569) PubChem (59284311) PubChem (59511080) PubChem (59897430) PubChem (59903654) PubChem (60009793) PubChem (60024420) PubChem (66639443) PubChem (66899541) PubChem (177390461) PubChem (177679009) PubChem (89970519) PubChem (3255) PubChem (8233) PubChem (9361) PubChem (90472408) PubChem (154401) PubChem (70897564) PubChem (71306958) PubChem (73265320) PubChem (73456721) PubChem (73946784) PubChem (456593) PubChem (467795) PubChem (489009) PubChem (86820632) PubChem (90473776) PubChem (90746906) PubChem (91434318) PubChem (91558259) PubChem (97293608) PubChem (99719271) PubChem (110189186) PubChem (6540620) PubChem (6602506) PubChem (6604221) PubChem (124226124) PubChem (124518166) PubChem (124604978) PubChem (124605145) PubChem (124605175) PubChem (124723146) PubChem (124798369) PubChem (124762348) PubChem (124822557) PubChem (9833120) PubChem (10032882) PubChem (6364614) PubChem (129009922) PubChem (129125718) PubChem (129445574) PubChem (129445576) PubChem (129666958) PubChem (10897911) PubChem (132274086) PubChem (97293607) PubChem (6604684) PubChem (6713919) PubChem (133126690) PubChem (133126790) PubChem (133550114) PubChem (133688268) PubChem (134081643) PubChem (134081274) PubChem (99719272) PubChem (134693955) PubChem (118725304) PubChem (11970254) PubChem (10034134) PubChem (12358519) PubChem (12358515) PubChem (12358508) PubChem (137705094) PubChem (124226125) PubChem (139247122) PubChem (124523502) PubChem (141945645) PubChem (124604979) PubChem (124605144) PubChem (124605146) PubChem (124716782) PubChem (124716783) PubChem (124723147) PubChem (124762349) PubChem (12358509) PubChem (12358517) PubChem (12966969) PubChem (15986867) PubChem (124822555) PubChem (124822558) PubChem (124870987) PubChem (146158524) PubChem (157254288) PubChem (163003493) PubChem (163003495) PubChem (165844830) PubChem (169440260) PubChem (126969058) PubChem (129010384) PubChem (172897573) PubChem (129119817) PubChem (129445575) PubChem (129627840) PubChem (129628729) PubChem (131665174) PubChem (133562871) PubChem (133602826) PubChem (134081264) PubChem (134693174) PubChem (135026875) PubChem (138113460) PubChem (138403276) PubChem (140886742) PubChem (141646830) PubChem (145774355) PubChem (155899868) PubChem (155900413) PubChem (161123720) PubChem (163003494) PubChem (163003496) PubChem (166604455) PubChem (166639762) PubChem (169289157) PubChem (171114703) PubChem (172897571) PubChem (16212992) PubChem (16213052) |
Sequence modifications
AN: 1 - 101 (UniProt: P0AG59)
BB: 1 - 119 (GenBank: 991970073)
| PDB | External Database | Details |
|---|---|---|
| Ala 36 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| A 120 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 56 |
| Total formula weight | 2198149.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 733.9 | |
| All* | Total formula weight | 2198883.3 |
