5JT7
tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 1-(2-((2-morpholinoethyl)amino)-1H-benzo[d]imidazol-6-yl)guanidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Queuine tRNA-ribosyltransferase | polymer | 386 | 42925.7 | 1 | UniProt (P28720) Pfam (PF01702) | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) | Guanine insertion enzyme,tRNA-guanine transglycosylase |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | N-(2-{[2-(morpholin-4-yl)ethyl]amino}-1H-benzimidazol-5-yl)guanidine | non-polymer | 303.4 | 1 | Chemie (6N2) | |||
| 5 | F (A) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
A: 1 - 386 (UniProt: P28720)
| PDB | External Database | Details |
|---|---|---|
| Lys 312 | Thr 312 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42925.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 553.0 | |
| All* | Total formula weight | 43478.7 |
