5JR8
Disposal of Iron by a Mutant form of Siderocalin NGAL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Neutrophil gelatinase-associated lipocalin | polymer | 178 | 20383.8 | 2 | UniProt (P80188) Pfam (PF00061) | Homo sapiens (Human) | NGAL,25 kDa alpha-2-microglobulin-related subunit of MMP-9,Lipocalin-2,Oncogene 24p3,Siderocalin LCN2,p25 |
| 2 | C, D, F (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 3 | E (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 178 (UniProt: P80188)
| PDB | External Database | Details |
|---|---|---|
| Ser 15 | Lys 35 | conflict |
| Glu 46 | Lys 66 | conflict |
| Asp 73 | Lys 93 | conflict |
| Asp 74 | Lys 94 | conflict |
| Gly 75 | Lys 95 | conflict |
| Gln 98 | Lys 118 | conflict |
| Phe 118 | His 138 | conflict |
| Gln 130 | Arg 150 | conflict |
| Gln 149 | Lys 169 | conflict |
| Asn 165 | His 185 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40767.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 377.0 | |
| All* | Total formula weight | 41144.7 |
