5JR3
Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with SAH and 4-methylumbelliferone
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Carminomycin 4-O-methyltransferase DnrK | polymer | 376 | 41000.4 | 3 | UniProt (Q06528) Pfam (PF00891) In PDB | Streptomyces peucetius | COMT,Anthracycline 4-O-methyltransferase |
2 | A, B, C | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 3 | Chemie (SAH) | |||
3 | A, B, C | 7-hydroxy-4-methyl-2H-chromen-2-one | non-polymer | 176.2 | 3 | Chemie (4MU) | |||
4 | A, B, C | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
5 | water | water | 18.0 | 835 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 356 (UniProt: Q06528)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 123001.2 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 2834.5 | |
All* | Total formula weight | 125835.7 |