5JQ1
Efficient targeting of the asialoglycoprotein receptor by polyvalent display of a compact galactosamine mimic
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Asialoglycoprotein receptor 1 | polymer | 145 | 17011.6 | 2 | UniProt (P07306) Pfam (PF00059) | Homo sapiens (Human) | ASGPR 1,C-type lectin domain family 4 member H1,Hepatic lectin H1,HL-1 |
2 | C, D, E, H, I... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
3 | F, J (A, B) | N-[(1S,2R,3R,4R,5S)-2,3-dihydroxy-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octan-4-yl]acetamide | non-polymer | 233.2 | 2 | Chemie (ZPF) | |||
4 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | L, M (A, B) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A, B: 147 - 290 (UniProt: P07306)
PDB | External Database | Details |
---|---|---|
Met 146 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 34023.1 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 742.4 | |
All* | Total formula weight | 34765.5 |