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5JQ1

Efficient targeting of the asialoglycoprotein receptor by polyvalent display of a compact galactosamine mimic

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Asialoglycoprotein receptor 1polymer14517011.62UniProt (P07306)
Pfam (PF00059)
Homo sapiens (Human)ASGPR 1,C-type lectin domain family 4 member H1,Hepatic lectin H1,HL-1
2C, D, E, H, I...
(A, B)
CALCIUM IONnon-polymer40.16Chemie (CA)
3F, J
(A, B)
N-[(1S,2R,3R,4R,5S)-2,3-dihydroxy-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octan-4-yl]acetamidenon-polymer233.22Chemie (ZPF)
4G
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5L, M
(A, B)
waterwater18.0146Chemie (HOH)
Sequence modifications
A, B: 147 - 290 (UniProt: P07306)
PDBExternal DatabaseDetails
Met 146-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight34023.1
Non-Polymers*Number of molecules9
Total formula weight742.4
All*Total formula weight34765.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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