5JPI
2.15 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with D-Eritadenine and NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Adenosylhomocysteinase | polymer | 498 | 56200.7 | 4 | UniProt (Q5CPH1) Pfam (PF05221) Pfam (PF00670) | Cryptosporidium parvum | |
| 2 | E, I, P, Y (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, J, Q, Z (A, B, C, D) | D-ERITADENINE | non-polymer | 253.2 | 4 | Chemie (DEA) | |||
| 4 | AA, G, H, K, L... (D, A, B, C) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | M, S, W (B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 6 | N, O, U, V (B, C) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 7 | T (C) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 8 | CA, X (D, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 9 | BA (D) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 10 | DA, EA, FA, GA (A, B, C, D) | water | water | 18.0 | 1223 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 495 (UniProt: Q5CPH1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 224802.7 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 5020.5 | |
| All* | Total formula weight | 229823.3 |
