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5JOH

CRYSTAL STRUCTURE OF CSN5(2-257) IN COMPLEX WITH CNS5i-1b

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
COP9 signalosome complex subunit 5polymer25728951.01UniProt (Q92905)
Pfam (PF01398)
Homo sapiens (Human)Signalosome subunit 5,Jun activation domain-binding protein 1
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
2'-chloro-6-[(5S,6S)-6-hydroxy-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl][1,1'-biphenyl]-3-carbonitrilenon-polymer363.81Chemie (6M3)
4D
(A)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
5E
(A)
waterwater18.029Chemie (HOH)
Sequence modifications
A: 2 - 257 (UniProt: Q92905)
PDBExternal DatabaseDetails
Gly 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28951.0
Non-Polymers*Number of molecules3
Total formula weight547.4
All*Total formula weight29498.4
*Water molecules are not included.

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PDB entries from 2026-01-21

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