5JN8
Crystal Structure for the complex of human carbonic anhydrase IV and acetazolamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Carbonic anhydrase 4 | polymer | 266 | 30364.5 | 4 | UniProt (P22748) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase IV,Carbonic anhydrase IV,CA-IV |
| 2 | DA, E, N, W (D, A, B, C) | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | non-polymer | 222.2 | 4 | Chemie (AZM) | |||
| 3 | EA, F, O, X (D, A, B, C) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | FA, G, GA, H, I... (D, A, B, C) | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 5 | AA, HA, K, L, T (C, D, A, B) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 6 | BA, CA, M, U, V (C, A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 7 | IA, JA, KA, LA (A, B, C, D) | water | water | 18.0 | 962 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 121457.9 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 3059.1 | |
| All* | Total formula weight | 124517.0 |
