5JKM
Binary crystal structure of positively and negatively supercharged variants Ftn(pos) and Ftn(neg) from human heavy chain ferritin (Mg acetate condition)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Ferritin heavy chain | polymer | 183 | 21499.2 | 6 | UniProt (P02794) Pfam (PF00210) In PDB | Homo sapiens (Human) | Ferritin H subunit,Cell proliferation-inducing gene 15 protein,Positively charged variant of human heavy chain ferritin |
2 | G, H, I, J, K... | Ferritin heavy chain | polymer | 183 | 21355.5 | 6 | UniProt (P02794) Pfam (PF00210) In PDB | Homo sapiens (Human) | Ferritin H subunit,Cell proliferation-inducing gene 15 protein,Negatively charged variant of human heavy chain ferritin |
3 | F, G, H, I, J... | FE (III) ION | non-polymer | 55.8 | 12 | Chemie (FE) | |||
4 | F, G, H, I, J... | MAGNESIUM ION | non-polymer | 24.3 | 17 | Chemie (MG) | |||
5 | A, E | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
6 | water | water | 18.0 | 1515 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 0 - 182 (UniProt: P02794)
G, H, I, J, K, L: 0 - 182 (UniProt: P02794)
PDB | External Database | Details |
---|---|---|
Lys 18 | Ala 19 | engineered mutation |
Arg 25 | Asn 26 | engineered mutation |
Gln 86 | Lys 87 | engineered mutation |
Lys 90 | Cys 91 | engineered mutation |
Arg 98 | Asn 99 | engineered mutation |
Lys 102 | Cys 103 | engineered mutation |
Lys 105 | His 106 | engineered mutation |
Lys 109 | Asn 110 | engineered mutation |
Lys 123 | Asp 124 | engineered mutation |
Arg 162 | Glu 163 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Glu 18 | Ala 19 | engineered mutation |
Gln 86 | Lys 87 | engineered mutation |
Glu 90 | Cys 91 | engineered mutation |
Glu 102 | Cys 103 | engineered mutation |
Glu 105 | His 106 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 257128.8 | |
Non-Polymers* | Number of molecules | 31 |
Total formula weight | 1267.5 | |
All* | Total formula weight | 258396.3 |