5JJU

Crystal structure of Rv2837c complexed with 5'-pApA and 5'-AMP

Replaces:  5CEU

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Uncharacterized protein Rv2837c	polymer	340	35756.7	2	UniProt (A5U6I9) Pfam (PF01368) Pfam (PF02272) UniProt (by SIFTS) (P71615)	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
2	C (C)	RNA (5'-R(P*AP*A)-3')	polymer	2	613.5	1		synthetic construct
3	D, E, F, G (A, B)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
4	H, I (B)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	2	Chemie (AMP)
5	J, K (A, B)	water	water		18.0	166	Chemie (HOH)

Sequence modifications

A, B: 11 - 336 (UniProt: A5U6I9)

PDB	External Database	Details
Leu 337	-	expression tag
Thr 338	-	expression tag
Arg 339	-	expression tag
Ala 340	-	expression tag
Pro 341	-	expression tag
Pro 342	-	expression tag
Pro 343	-	expression tag
Pro 344	-	expression tag
Pro 345	-	expression tag
Leu 346	-	expression tag
Arg 347	-	expression tag
Ser 348	-	expression tag
Gly 349	-	expression tag
Cys 350	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	72126.8
Non-Polymers*	Number of molecules	6
	Total formula weight	914.2
All*	Total formula weight	73041.0

*Water molecules are not included.