5JJA
Crystal structure of a PP2A B56gamma/BubR1 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | polymer | 352 | 41366.9 | 2 | UniProt (Q13362) Pfam (PF01603) In PDB | Homo sapiens (Human) | PP2A B subunit isoform B'-gamma,PP2A B subunit isoform B56-gamma,PP2A B subunit isoform PR61-gamma,PP2A B subunit isoform R5-gamma,Renal carcinoma antigen NY-REN-29 |
| 2 | C, D | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | polymer | 75 | 7999.6 | 2 | UniProt (O60566) In PDB | Homo sapiens (Human) | MAD3/BUB1-related protein kinase,hBUBR1,Mitotic checkpoint kinase MAD3L,Protein SSK1 |
| 3 | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence modifications
A, B: 30 - 380 (UniProt: Q13362)
C, D: 647 - 720 (UniProt: O60566)
| PDB | External Database | Details |
|---|---|---|
| Gly 29 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 646 | - | expression tag |
| Asp 670 | Ser 684 | engineered mutation |
| Asp 676 | Ser 690 | engineered mutation |
| Asp 680 | Thr 694 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 98733.0 | |
| All* | Total formula weight | 98733.0 |
