5JGT
Human carbonic anhydrase II (F131Y/L198A) complexed with 1,3-thiazole-2-sulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Carbonic anhydrase 2 | polymer | 259 | 29115.8 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
| 2 | B (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D (B) | 1,3-thiazole-2-sulfonamide | non-polymer | 164.2 | 2 | Chemie (EVI) | |||
| 4 | E (B) | water | water | 18.0 | 423 | Chemie (HOH) |
Sequence modifications
B: 3 - 260 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | - | expression tag |
| Tyr 130 | Phe 130 | conflict |
| Ala 197 | Leu 197 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29115.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 393.8 | |
| All* | Total formula weight | 29509.6 |
