5JG3
Human carbonic anhydrase II (121T/N67Q) complexed with benzo[d]thiazole-2-sulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Carbonic anhydrase 2 | polymer | 259 | 29157.9 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
| 2 | B, C (B) | 1,3-benzothiazole-2-sulfonamide | non-polymer | 214.3 | 2 | Chemie (EVF) | |||
| 3 | D (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | E (B) | water | water | 18.0 | 417 | Chemie (HOH) |
Sequence modifications
B: 3 - 260 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | - | expression tag |
| Gln 67 | Asn 67 | engineered mutation |
| Thr 121 | Val 121 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29157.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 493.9 | |
| All* | Total formula weight | 29651.8 |
