5JFO
Structure of the M.tuberculosis enoyl-reductase InhA in complex with GSK625
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 269 | 28554.8 | 4 | UniProt (P9WGR1) Pfam (PF13561) In PDB | Mycobacterium tuberculosis | NADH-dependent enoyl-ACP reductase |
2 | A, B, C, D | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
3 | A, B, C, D | N-{1-[(2-chloro-6-fluorophenyl)methyl]-1H-pyrazol-3-yl}-5-[(1S)-1-(3-methyl-1H-pyrazol-1-yl)ethyl]-1,3,4-thiadiazol-2-amine | non-polymer | 417.9 | 4 | Chemie (6KA) | |||
4 | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 114219.1 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 4325.3 | |
All* | Total formula weight | 118544.4 |