5JFO

Structure of the M.tuberculosis enoyl-reductase InhA in complex with GSK625

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Enoyl-[acyl-carrier-protein] reductase [NADH]	polymer	269	28554.8	4	UniProt (P9WGR1) Pfam (PF13561)	Mycobacterium tuberculosis	NADH-dependent enoyl-ACP reductase
2	E, G, I, K (A, B, C, D)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	4	Chemie (NAD)
3	F, H, J, L (A, B, C, D)	N-{1-[(2-chloro-6-fluorophenyl)methyl]-1H-pyrazol-3-yl}-5-[(1S)-1-(3-methyl-1H-pyrazol-1-yl)ethyl]-1,3,4-thiadiazol-2-amine	non-polymer		417.9	4	Chemie (6KA)
4	M, N, O, P (A, B, C, D)	water	water		18.0	55	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	114219.1
Non-Polymers*	Number of molecules	8
	Total formula weight	4325.3
All*	Total formula weight	118544.4

*Water molecules are not included.