5JFG
Structure of humanised RadA-mutant humRadA22F in complex with peptide FHTA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA repair and recombination protein RadA | polymer | 231 | 25398.9 | 1 | UniProt (O74036) Pfam (PF08423) | Pyrococcus furiosus | |
| 2 | B (B) | PEPTIDE FHTA | polymer | 6 | 515.6 | 1 | SYNTHETIC CONSTRUCT | ||
| 3 | C, D, E (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 4 | F (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A: 108 - 349 (UniProt: O74036)
| PDB | External Database | Details |
|---|---|---|
| Met 107 | - | initiating methionine |
| Ala 168 | Val 168 | engineered mutation |
| Met 169 | Ile 169 | engineered mutation |
| Tyr 170 | Trp 170 | engineered mutation |
| Leu 182 | Ile 182 | engineered mutation |
| Asp 198 | Lys 198 | engineered mutation |
| Asn 199 | His 199 | engineered mutation |
| Val 200 | Ile 200 | engineered mutation |
| Ala 201 | Tyr 201 | engineered mutation |
| Tyr 202 | Val 202 | engineered mutation |
| Met 221 | Lys 221 | engineered mutation |
| - | Arg 288 | deletion |
| - | Pro 289 | deletion |
| - | Asp 290 | deletion |
| - | Ala 291 | deletion |
| - | Phe 292 | deletion |
| - | Phe 293 | deletion |
| - | Gly 294 | deletion |
| - | Asp 295 | deletion |
| - | Pro 296 | deletion |
| - | Thr 297 | deletion |
| - | Arg 298 | deletion |
| - | Pro 299 | deletion |
| Asn 300 | Ile 300 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25914.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 274.5 | |
| All* | Total formula weight | 26188.9 |
