5JFE
Flavin-dependent thymidylate synthase with H2-dUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thymidylate synthase ThyX | polymer | 232 | 27503.7 | 1 | UniProt (Q9WYT0) Pfam (PF02511) | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) | TSase |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C (A) | 2'-deoxy-5'-uridylic acid | non-polymer | 310.2 | 1 | Chemie (UMC) | |||
| 4 | D, E, F, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | I (A) | water | water | 18.0 | 110 | Chemie (HOH) |
Sequence modifications
A: 1 - 220 (UniProt: Q9WYT0)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | initiating methionine |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Ile -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27503.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1406.1 | |
| All* | Total formula weight | 28909.8 |
