5JFD
Thrombin in complex with (S)-N-(2-(aminomethyl)-5-chlorobenzyl)-1-((benzylsulfonyl)-D-arginyl)pyrrolidine-2-carboxamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | Prothrombin | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | Homo sapiens (Human) | Coagulation factor II |
| 2 | H | Prothrombin | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | Homo sapiens (Human) | Coagulation factor II |
| 3 | I | Hirudin variant-2 | polymer | 12 | 1548.6 | 1 | UniProt (P09945) In PDB | Hirudo medicinalis | |
| 4 | H | (2S)-N-[[2-(aminomethyl)-5-chloro-phenyl]methyl]-1-[(2R)-5-carbamimidamido-2-(phenylmethylsulfonylamino)pentanoyl]pyrrolidine-2-carboxamide | non-polymer | 578.1 | 1 | BIRD (PRD_000667) Chemie (2TS) | |||
| 5 | H | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | H | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | H | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 8 | H | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 9 | water | water | 18.0 | 264 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35425.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1107.6 | |
| All* | Total formula weight | 36533.0 |
