5JEI

Crystal structure of the GluA2 LBD in complex with FW

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Glutamate receptor 2,Glutamate receptor 2	polymer	264	29282.7	1	UniProt (P19491) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus (Rat)	GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2	B (A)	2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID	non-polymer		217.2	1	Chemie (FWD)
3	C, D (A)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	E, H (A)	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
5	F, L, N (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	3	Chemie (PEG)
6	G (A)	2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL	non-polymer		164.2	1	Chemie (TOE)
7	I (A)	2-(2-METHOXYETHOXY)ETHANOL	non-polymer		120.1	1	Chemie (PG0)
8	J, K (A)	2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL	non-polymer		208.3	2	Chemie (ETE)
9	M (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
10	O (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
11	P (A)	water	water		18.0	375	Chemie (HOH)

Sequence modifications

A: 3 - 117 (UniProt: P19491)

PDB	External Database	Details
Gly 1	-	expression tag
Ala 2	-	expression tag

A: 120 - 264 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker
Cys 154	Val 687	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29282.7
Non-Polymers*	Number of molecules	14
	Total formula weight	1899.8
All*	Total formula weight	31182.6

*Water molecules are not included.