5J8O
Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Programmed cell death 1 ligand 1 | polymer | 124 | 14126.2 | 2 | UniProt (Q9NZQ7) Pfam (PF07686) | Homo sapiens (Human) | Programmed death ligand 1,B7 homolog 1,B7-H1 |
| 2 | C (A) | (2R)-1-({3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl}methyl)piperidine-2-carboxylic acid | non-polymer | 494.4 | 1 | Chemie (6GZ) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, B: 18 - 134 (UniProt: Q9NZQ7)
| PDB | External Database | Details |
|---|---|---|
| Ala 135 | - | expression tag |
| Ala 136 | - | expression tag |
| Ala 137 | - | expression tag |
| Leu 138 | - | expression tag |
| Glu 139 | - | expression tag |
| His 140 | - | expression tag |
| His 141 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28252.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 494.4 | |
| All* | Total formula weight | 28746.8 |
