5J8C
Human MOF C316S, E350Q crystal structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone acetyltransferase KAT8 | polymer | 307 | 36121.5 | 1 | UniProt (Q9H7Z6) Pfam (PF17772) Pfam (PF01853) | Homo sapiens (Human) | Lysine acetyltransferase 8,MOZ,YBF2/SAS3,SAS2 and TIP60 protein 1,hMOF |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | E, F (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | G (A) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A: 177 - 458 (UniProt: Q9H7Z6)
| PDB | External Database | Details |
|---|---|---|
| Met 152 | - | initiating methionine |
| Gly 153 | - | expression tag |
| Ser 154 | - | expression tag |
| Ser 155 | - | expression tag |
| His 156 | - | expression tag |
| His 157 | - | expression tag |
| His 158 | - | expression tag |
| His 159 | - | expression tag |
| His 160 | - | expression tag |
| His 161 | - | expression tag |
| Asp 162 | - | expression tag |
| Tyr 163 | - | expression tag |
| Asp 164 | - | expression tag |
| Ile 165 | - | expression tag |
| Pro 166 | - | expression tag |
| Thr 167 | - | expression tag |
| Thr 168 | - | expression tag |
| Glu 169 | - | expression tag |
| Asn 170 | - | expression tag |
| Leu 171 | - | expression tag |
| Tyr 172 | - | expression tag |
| Phe 173 | - | expression tag |
| Gln 174 | - | expression tag |
| Gly 175 | - | expression tag |
| Ser 176 | - | expression tag |
| Ser 316 | Cys 316 | engineered mutation |
| Gln 350 | Glu 350 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36121.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 182.3 | |
| All* | Total formula weight | 36303.8 |
