5J89

Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, A, D, B	Programmed cell death 1 ligand 1	polymer	144	16734.3	4	UniProt (Q9NZQ7) Pfam (PF07686) In PDB	Homo sapiens (Human)	Programmed death ligand 1,B7 homolog 1,B7-H1
2	C, B	N-{2-[({2-methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]pyridin-3-yl}methyl)amino]ethyl}acetamide	non-polymer		419.5	2	Chemie (6GX)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4		water	water		18.0	208	Chemie (HOH)

Sequence modifications

C, A, D, B: 2 - 134 (UniProt: Q9NZQ7)

PDB	External Database	Details
Ala 135	-	expression tag
Ala 136	-	expression tag
Ala 137	-	expression tag
Leu 138	-	expression tag
Glu 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	66937.0
Non-Polymers*	Number of molecules	3
	Total formula weight	901.1
All*	Total formula weight	67838.1

*Water molecules are not included.