5J5J
Crystal structure of a chimera of human Desmocollin-2 EC1 and human Desmoglein-2 EC2-EC5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Desmocollin-2,Desmoglein-2 | polymer | 557 | 62691.9 | 1 | UniProt (Q02487) UniProt (Q14126) Pfam (PF00028) | Homo sapiens (Human) | Cadherin family member 2,Desmocollin-3,Desmosomal glycoprotein II,Desmosomal glycoprotein III,Cadherin family member 5,HDGC |
| 2 | B (B) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1479.3 | 1 | In PDB GlyTouCan (G88310KZ) | |||
| 3 | C (C) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 1 | In PDB GlyTouCan (G82348BZ) | |||
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E, F, G (A) | alpha-D-mannopyranose | non-polymer | 180.2 | 3 | Chemie (MAN) | |||
| 6 | H, I (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | J, K, L, M, N... (A) | CALCIUM ION | non-polymer | 40.1 | 11 | Chemie (CA) | |||
| 8 | U, V (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 9 | W (A) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A: 1 - 100 (UniProt: Q02487)
A: 101 - 550 (UniProt: Q14126)
A: 101 - 550 (UniProt: Q14126)
| PDB | External Database | Details |
|---|---|---|
| Ala 551 | - | expression tag |
| His 552 | - | expression tag |
| His 553 | - | expression tag |
| His 554 | - | expression tag |
| His 555 | - | expression tag |
| His 556 | - | expression tag |
| His 557 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 62691.9 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2960.7 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 1494.6 | |
| All* | Total formula weight | 67147.3 |
