5J48
PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-pCPT-cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cGMP-dependent protein kinase 1 | polymer | 135 | 14986.7 | 2 | UniProt (Q13976) Pfam (PF00027) | Homo sapiens (Human) | cGK1,cGMP-dependent protein kinase I,cGKI |
| 2 | C, D, E, G, I... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 3 | F, M (A, B) | 2-amino-8-[(4-chlorophenyl)sulfanyl]-9-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-3,9-dihydro-6H-purin-6-one | non-polymer | 487.8 | 2 | Chemie (6FW) | |||
| 4 | H, O (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | N (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | P, Q (A, B) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence modifications
A, B: 219 - 351 (UniProt: Q13976)
| PDB | External Database | Details |
|---|---|---|
| Gly 217 | - | expression tag |
| Ser 218 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29973.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1558.2 | |
| All* | Total formula weight | 31531.7 |
