5J3V

Crystal structure of human Karyopherin-beta2 bound to the histone H3 tail

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, B)	Transportin-1,Transportin-1	polymer	854	96766.8	2	UniProt (Q92973) Pfam (PF03810) Pfam (PF02985) Pfam (PF13513)	Homo sapiens (Human)	Importin beta-2,Karyopherin beta-2,M9 region interaction protein,MIP,Importin beta-2,Karyopherin beta-2,M9 region interaction protein,MIP
2	B, D (C, D)	Histone H3	polymer	17	1788.1	2	UniProt (by SIFTS) (P68431)	Homo sapiens

Sequence modifications

A, B: 1 - 359 (UniProt: Q92973)
A, B: 367 - 890 (UniProt: Q92973)

PDB	External Database	Details
Gly 360	-	linker
Gly 361	-	linker
Ser 362	-	linker
Gly 363	-	linker
Gly 364	-	linker
Ser 365	-	linker
Gly 366	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	197109.8
All*	Total formula weight	197109.8

*Water molecules are not included.