5J2X
Crystal Structure of Hsp90-alpha N-domain in complex with 5-(5-Bromo-2,4-dihydroxy-phenyl)-4-(2-fluoro-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat shock protein HSP 90-alpha | polymer | 209 | 23334.5 | 1 | UniProt (P07900) Pfam (PF13589) | Homo sapiens (Human) | Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38 |
| 2 | B (A) | 5-(5-Bromo-2,4-dihydroxy-phenyl)-4-(2-fluoro-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one | non-polymer | 366.1 | 1 | Chemie (6DL) | |||
| 3 | C (A) | water | water | 18.0 | 306 | Chemie (HOH) |
Sequence modifications
A: 17 - 224 (UniProt: P07900)
| PDB | External Database | Details |
|---|---|---|
| Ala 16 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23334.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 366.1 | |
| All* | Total formula weight | 23700.6 |
