5J06
Structure of the immune receptor CD33 in complex with 3'-sialyllactose
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Myeloid cell surface antigen CD33 | polymer | 224 | 25052.1 | 4 | UniProt (P20138) Pfam (PF07686) Pfam (PF00047) In PDB | Homo sapiens (Human) | Sialic acid-binding Ig-like lectin 3,Siglec-3,gp67 |
2 | E | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | branched | 471.4 | 1 | In PDB GlyTouCan (G30207PZ) | |||
3 | A, B, C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 13 | Chemie (NAG) | |||
4 | B, C | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 2 | Chemie (PG0) | |||
5 | D | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 1 | Chemie (SIA) | |||
6 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 21 - 232 (UniProt: P20138)
PDB | External Database | Details |
---|---|---|
Glu 18 | - | expression tag |
Thr 19 | - | expression tag |
Gly 20 | - | expression tag |
Gly 69 | Arg 69 | variant |
Gly 233 | - | expression tag |
Thr 234 | - | expression tag |
Lys 235 | - | expression tag |
His 236 | - | expression tag |
His 237 | - | expression tag |
His 238 | - | expression tag |
His 239 | - | expression tag |
His 240 | - | expression tag |
His 241 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 100208.6 | |
Branched | Number of molecules | 1 |
Total formula weight | 471.4 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 3425.3 | |
All* | Total formula weight | 104105.2 |