5IZL

The crystal structure of human eEFSec in complex with GDPCP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Selenocysteine-specific elongation factor	polymer	616	67564.0	2	UniProt (P57772) Pfam (PF00009) Pfam (PF03144) Pfam (PF21208) Pfam (PF21131)	Homo sapiens (Human)	Elongation factor sec,Eukaryotic elongation factor,selenocysteine-tRNA-specific
2	C, E (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	D, F (A, B)	PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER	non-polymer		521.2	2	Chemie (GCP)
4	G, H (A, B)	water	water		18.0	31	Chemie (HOH)

Sequence modifications

A, B: 1 - 596 (UniProt: P57772)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	135127.9
Non-Polymers*	Number of molecules	4
	Total formula weight	1091.0
All*	Total formula weight	136218.9

*Water molecules are not included.