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5IWT

Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of gadolinium

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Transient receptor potential cation channel subfamily V member 6polymer67277148.51UniProt (Q9R186)
Pfam (PF12796)
Pfam (PF00520)
Rattus norvegicus (Rat)TrpV6,Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2
2B, C
(A)
GADOLINIUM ATOMnon-polymer157.32Chemie (GD)
3D
(A)
6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACIDnon-polymer214.31Chemie (DTB)
Sequence modifications
A: 1 - 669 (UniProt: Q9R186)
PDBExternal DatabaseDetails
Tyr 62Ile 102engineered mutation
Asn 92Leu 132engineered mutation
Gln 96Met 136engineered mutation
Gln 495Leu 535engineered mutation
Val 670-expression tag
Pro 671-expression tag
Arg 672-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight77148.5
Non-Polymers*Number of molecules3
Total formula weight528.8
All*Total formula weight77677.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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