5IW6
anti-CD20 monoclonal antibody Fc fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ig gamma-1 chain C region | polymer | 209 | 23723.8 | 1 | UniProt (P01857) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B (B) | Ig gamma-1 chain C region | polymer | 205 | 23425.5 | 1 | UniProt (P01857) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C, D (C, D) | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1479.3 | 2 | In PDB GlyTouCan (G32253EE) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A: 259 - 467 (UniProt: P01857)
B: 262 - 466 (UniProt: P01857)
| PDB | External Database | Details |
|---|---|---|
| Glu 379 | Asp 239 | engineered mutation |
| Met 381 | Leu 241 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Glu 379 | Asp 239 | engineered mutation |
| Met 381 | Leu 241 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47149.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2958.7 | |
| All* | Total formula weight | 50108.0 |
