5IW3
anti-CD20 monoclonal antibody Fc fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Ig gamma-1 chain C region | polymer | 208 | 23636.7 | 1 | UniProt (P01857) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 2 | B | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1479.3 | 1 | In PDB GlyTouCan (G89993FE) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | A | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 245 | Chemie (HOH) |
Sequence modifications
A: 259 - 466 (UniProt: P01857)
| PDB | External Database | Details |
|---|---|---|
| Glu 379 | Asp 239 | engineered mutation |
| Met 381 | Leu 241 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23636.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1479.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 406.3 | |
| All* | Total formula weight | 25522.3 |
