5IVV
Linked KDM5A Jmj Domain Bound to the Inhibitor N12 [3-((1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)amino)isonicotinic acid]
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Lysine-specific demethylase 5A | polymer | 330 | 37944.8 | 1 | UniProt (P29375) Pfam (PF02375) Pfam (PF02373) In PDB | Homo sapiens (Human) | Histone demethylase JARID1A,Jumonji/ARID domain-containing protein 1A,Retinoblastoma-binding protein 2,RBBP-2 |
| 2 | A | 3-[(1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)amino]pyridine-4-carboxylic acid | non-polymer | 268.3 | 1 | Chemie (6EN) | |||
| 3 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 4 | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
A: 1 - 347 (UniProt: P29375)
A: 348 - 588 (UniProt: P29375)
| PDB | External Database | Details |
|---|---|---|
| His -1 | - | expression tag |
| Asn 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37944.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 323.2 | |
| All* | Total formula weight | 38268.0 |
