5IS6
Crystal structure of mouse CARM1 in complex with Sinefungin at 2.0 Angstroms resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Histone-arginine methyltransferase CARM1 | polymer | 361 | 40850.5 | 4 | UniProt (Q9WVG6) Pfam (PF06325) Pfam (PF22528) | Mus musculus (Mouse) | Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4 |
| 2 | E, L, R (A, B, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) | |||
| 3 | F, M, N, S, T... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | G, H, V (A, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 5 | AA, I, J, O, P... (D, A, B, C) | 1,2-DIMETHOXYETHANE | non-polymer | 90.1 | 6 | Chemie (DXE) | |||
| 6 | BA, K, Q, X (D, A, B, C) | SINEFUNGIN | non-polymer | 381.4 | 4 | Chemie (SFG) | |||
| 7 | CA, DA, EA, FA (A, B, C, D) | water | water | 18.0 | 1036 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 130 - 487 (UniProt: Q9WVG6)
| PDB | External Database | Details |
|---|---|---|
| Gly 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 163401.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 3463.9 | |
| All* | Total formula weight | 166865.7 |
