5IQH
Aminoglycoside Phosphotransferase (2'')-Ia (CTD of AAC(6')-Ie/APH(2'')-Ia) S214A mutant in complex with GMPPNP and Magnesium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Bifunctional AAC/APH | polymer | 305 | 35932.2 | 4 | UniProt (P0A0C1) Pfam (PF01636) In PDB | Staphylococcus aureus | |
| 2 | A, B, C, D | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 4 | Chemie (GNP) | |||
| 3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 9 | Chemie (MG) | |||
| 4 | A, B, C | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | A, B, D | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 967 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 175 - 479 (UniProt: P0A0C1)
| PDB | External Database | Details |
|---|---|---|
| Ala 214 | Ser 214 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 143728.8 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2690.2 | |
| All* | Total formula weight | 146419.0 |
