5IOH

RepoMan-PP1a (protein phosphatase 1, alpha isoform) holoenzyme complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	polymer	299	34162.1	2	UniProt (P62136) Pfam (PF16891) Pfam (PF00149)	Homo sapiens (Human)	PP-1A
2	B, D (B, D)	Cell division cycle-associated protein 2	polymer	64	7023.1	2	UniProt (Q69YH5) Pfam (PF15276)	Homo sapiens (Human)	Recruits PP1 onto mitotic chromatin at anaphase protein,Repo-Man
3	E, F, G, H (A, B, C, D)	water	water		18.0	152	Chemie (HOH)

Sequence modifications

A, C: 7 - 300 (UniProt: P62136)

PDB	External Database	Details
Gly 2	-	expression tag
His 3	-	expression tag
Met 4	-	expression tag
Gly 5	-	expression tag
Ser 6	-	expression tag

B, D: 383 - 441 (UniProt: Q69YH5)

PDB	External Database	Details
Gly 378	-	expression tag
Ala 379	-	expression tag
Met 380	-	expression tag
Gly 381	-	expression tag
Tyr 382	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	82370.4
All*	Total formula weight	82370.4

*Water molecules are not included.