5ING

A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender unit

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Putative carboxyl transferase	polymer	570	62409.8	6	UniProt (A0ACI9) Pfam (PF01039)	Streptomyces ambofaciens ATCC 23877	Putative propionyl-CoA carboxylase
2	G, H, I, J, K... (A, B, C, D, E...)	water	water		18.0	936	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 2 - 532 (UniProt: A0ACI9)

PDB	External Database	Details
Mse -37	-	initiating methionine
Gly -36	-	expression tag
Ser -35	-	expression tag
Ser -34	-	expression tag
His -33	-	expression tag
His -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
Ser -27	-	expression tag
Ser -26	-	expression tag
Gly -25	-	expression tag
Leu -24	-	expression tag
Val -23	-	expression tag
Pro -22	-	expression tag
Arg -21	-	expression tag
Gly -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
Mse -17	-	expression tag
Ala -16	-	expression tag
Ser -15	-	expression tag
Asp -14	-	expression tag
Ser -13	-	expression tag
Thr -12	-	expression tag
Glu -11	-	expression tag
Asn -10	-	expression tag
Leu -9	-	expression tag
Tyr -8	-	expression tag
Phe -7	-	expression tag
Gln -6	-	expression tag
Gly -5	-	expression tag
Ile -4	-	expression tag
Asp -3	-	expression tag
Pro -2	-	expression tag
Phe -1	-	expression tag
Thr 0	-	expression tag
Mse 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	374458.9
All*	Total formula weight	374458.9

*Water molecules are not included.