5IM4
Crystal structure of designed two-component self-assembling icosahedral cage I52-32
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E, C, B, D... | 6,7-dimethyl-8-ribityllumazine synthase | polymer | 162 | 18101.1 | 20 | UniProt (A0A0A3CUI3) In PDB | Candida albicans P37005 | DMRL synthase |
2 | F, H, G, I, J... | Phosphotransferase system, mannose/fructose-specific component IIA | polymer | 138 | 15164.0 | 20 | UniProt (Q8RD55) Pfam (PF03610) In PDB | Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) |
Sequence modifications
A, E, C, B, D, K, L, N, M, O, U, V, X, W, Y, e, f, h, g, i: 12 - 164 (UniProt: A0A0A3CUI3)
F, H, G, I, J, P, Q, S, R, T, b, d, c, Z, a, j, k, m, l, n: 1 - 136 (UniProt: Q8RD55)
PDB | External Database | Details |
---|---|---|
Met 11 | - | expression tag |
Leu 29 | Arg 71 | engineered mutation |
Glu 30 | Lys 72 | engineered mutation |
Ala 33 | Asp 75 | engineered mutation |
Ile 40 | Val 82 | engineered mutation |
Ala 50 | Glu 92 | engineered mutation |
Leu 165 | - | expression tag |
Glu 166 | - | expression tag |
His 167 | - | expression tag |
His 168 | - | expression tag |
His 169 | - | expression tag |
His 170 | - | expression tag |
His 171 | - | expression tag |
His 172 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met -1 | - | expression tag |
Gly 0 | - | expression tag |
Lys 45 | Val 45 | engineered mutation |
Ala 47 | Arg 47 | engineered mutation |
Met 51 | Glu 51 | engineered mutation |
Arg 52 | Lys 52 | engineered mutation |
Ile 55 | Lys 55 | engineered mutation |
Ala 56 | Glu 56 | engineered mutation |
Ala 59 | Gln 59 | engineered mutation |
Glu 81 | Ser 81 | engineered mutation |
Thr 85 | Glu 85 | engineered mutation |
Phe 86 | Tyr 86 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 40 |
Total formula weight | 665301.8 | |
All* | Total formula weight | 665301.8 |