5IHC
MELK in complex with NVS-MELK12B
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Maternal embryonic leucine zipper kinase | polymer | 335 | 38959.1 | 1 | UniProt (Q14680) Pfam (PF00069) Pfam (PF21594) In PDB | Homo sapiens (Human) | hMELK,Protein kinase Eg3,pEg3 kinase,Protein kinase PK38,hPK38,Tyrosine-protein kinase MELK |
2 | A | 4-[1-(2-fluorophenyl)-1H-pyrazol-4-yl]-3-[(piperidin-4-yl)methoxy]pyridine | non-polymer | 352.4 | 1 | Chemie (6BB) | |||
3 | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 3 - 330 (UniProt: Q14680)
PDB | External Database | Details |
---|---|---|
Met 2 | - | initiating methionine |
His 331 | - | expression tag |
His 332 | - | expression tag |
His 333 | - | expression tag |
His 334 | - | expression tag |
His 335 | - | expression tag |
His 336 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 38959.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 352.4 | |
All* | Total formula weight | 39311.5 |