5IGL

Crystal structure of the second bromodomain of human TAF1L in complex with bromosporine (BSP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Transcription initiation factor TFIID subunit 1-like	polymer	155	18023.3	1	UniProt (Q8IZX4) Pfam (PF00439)	Homo sapiens (Human)	TAF(II)210,TBP-associated factor 1-like,TBP-associated factor 210 kDa,Transcription initiation factor TFIID 210 kDa subunit
2	B (A)	Bromosporine	non-polymer		404.4	1	Chemie (BMF)
3	C (A)	water	water		18.0	25	Chemie (HOH)

Sequence modifications

A: 1523 - 1654 (UniProt: Q8IZX4)

PDB	External Database	Details
Met 1500	-	initiating methionine
His 1501	-	expression tag
His 1502	-	expression tag
His 1503	-	expression tag
His 1504	-	expression tag
His 1505	-	expression tag
His 1506	-	expression tag
Ser 1507	-	expression tag
Ser 1508	-	expression tag
Gly 1509	-	expression tag
Val 1510	-	expression tag
Asp 1511	-	expression tag
Leu 1512	-	expression tag
Gly 1513	-	expression tag
Thr 1514	-	expression tag
Glu 1515	-	expression tag
Asn 1516	-	expression tag
Leu 1517	-	expression tag
Tyr 1518	-	expression tag
Phe 1519	-	expression tag
Gln 1520	-	expression tag
Ser 1521	-	expression tag
Met 1522	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	18023.3
Non-Polymers*	Number of molecules	1
	Total formula weight	404.4
All*	Total formula weight	18427.7

*Water molecules are not included.