5IFW
Quantitative interaction mapping reveals an extended ubiquitin regulatory domain in ASPL that disrupts functional p97 hexamers and induces cell death
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tether containing UBX domain for GLUT4 | polymer | 188 | 21356.4 | 1 | UniProt (Q9BZE9) Pfam (PF00789) | Homo sapiens (Human) | Alveolar soft part sarcoma chromosomal region candidate gene 1 protein,Alveolar soft part sarcoma locus,Renal papillary cell carcinoma protein 17,UBX domain-containing protein 9 |
| 2 | B (B) | Transitional endoplasmic reticulum ATPase | polymer | 807 | 89449.8 | 1 | UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862) | Homo sapiens (Human) | TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP |
| 3 | C, D (B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
B: 2 - 806 (UniProt: P55072)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110806.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 854.4 | |
| All* | Total formula weight | 111660.5 |
