5IFU
Crystal Structure of Prolyl-tRNA synthetase (ProRS, Proline--tRNA ligase) from Plasmodium falciparum in complex with Glyburide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Proline--tRNA ligase | polymer | 506 | 58986.5 | 2 | UniProt (Q8I5R7) Pfam (PF00587) Pfam (PF03129) Pfam (PF09180) | Plasmodium falciparum (isolate 3D7) | Prolyl-tRNA synthetase,ProRS |
| 2 | C, P (A, B) | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide | non-polymer | 494.0 | 2 | Chemie (GBM) | |||
| 3 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | E, F, G, H, I... (A, B) | FORMIC ACID | non-polymer | 46.0 | 14 | Chemie (FMT) | |||
| 5 | O, U (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | V, W (A, B) | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence modifications
A, B: 249 - 746 (UniProt: Q8I5R7)
| PDB | External Database | Details |
|---|---|---|
| Met 241 | - | expression tag |
| Ala 242 | - | expression tag |
| His 243 | - | expression tag |
| His 244 | - | expression tag |
| His 245 | - | expression tag |
| His 246 | - | expression tag |
| His 247 | - | expression tag |
| His 248 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 117973.0 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 1791.9 | |
| All* | Total formula weight | 119764.9 |
