5IF2
Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-576 (5,6-dichloro-1H-1,3-benzodiazol-2-yl)methanol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Polymerase acidic protein | polymer | 464 | 53096.7 | 1 | UniProt (P15659) Pfam (PF00603) In PDB | Influenza A virus (strain A/Wilson-Smith/1933 H1N1) | RNA-directed RNA polymerase subunit P2 |
2 | A | (5,6-dichloro-1H-benzimidazol-2-yl)methanol | non-polymer | 217.1 | 1 | Chemie (6B1) | |||
3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
5 | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A: 254 - 716 (UniProt: P15659)
PDB | External Database | Details |
---|---|---|
Gly 253 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 53096.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 330.6 | |
All* | Total formula weight | 53427.4 |