5IEG
Murine endoplasmic reticulum alpha-glucosidase II with N-9'-methoxynonyl-1-deoxynojirimycin.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neutral alpha-glucosidase AB | polymer | 914 | 103819.0 | 1 | UniProt (Q8BHN3) Pfam (PF13802) Pfam (PF01055) Pfam (PF21365) | Mus musculus (Mouse) | Alpha-glucosidase 2,Glucosidase II subunit alpha |
| 2 | B (B) | Glucosidase 2 subunit beta | polymer | 88 | 9568.3 | 1 | UniProt (O08795) Pfam (PF12999) | Mus musculus (Mouse) | 80K-H protein,Glucosidase II subunit beta,Protein kinase C substrate 60.1 kDa protein heavy chain,PKCSH |
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D (A) | N-9'-methoxynonyl-1-deoxynojirimycin | non-polymer | 319.4 | 1 | Chemie (6A9) | |||
| 5 | E, F, G, H, I (A) | FORMIC ACID | non-polymer | 46.0 | 5 | Chemie (FMT) | |||
| 6 | J, K, L, P (A) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 4 | Chemie (P6G) | |||
| 7 | M (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 8 | N, O, S (A, B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) | |||
| 9 | Q, R (B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 10 | T, U (A, B) | water | water | 18.0 | 490 | Chemie (HOH) |
Sequence modifications
A: 33 - 966 (UniProt: Q8BHN3)
| PDB | External Database | Details |
|---|---|---|
| - | Phe 188 | deletion |
| - | Ser 189 | deletion |
| - | Asp 190 | deletion |
| - | Lys 191 | deletion |
| - | Val 192 | deletion |
| - | Ser 193 | deletion |
| - | Leu 194 | deletion |
| - | Ala 195 | deletion |
| - | Leu 196 | deletion |
| - | Gly 197 | deletion |
| - | Ser 198 | deletion |
| - | Val 199 | deletion |
| - | Trp 200 | deletion |
| - | Asp 201 | deletion |
| - | Lys 202 | deletion |
| - | Ile 203 | deletion |
| - | Lys 204 | deletion |
| - | Asn 205 | deletion |
| - | Leu 206 | deletion |
| - | Phe 207 | deletion |
| - | Ser 208 | deletion |
| - | Arg 209 | deletion |
| Ala 967 | - | expression tag |
| Ser 968 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 113387.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2419.9 | |
| All* | Total formula weight | 116231.5 |
