5IE7
Crystal structure of a lactonase double mutant in complex with substrate b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Zearalenone hydrolase | polymer | 264 | 28801.6 | 3 | UniProt (Q8NKB0) | Clonostachys rosea | lactonase |
| 2 | D, E (A, B) | (3S,7S,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one | non-polymer | 320.4 | 2 | Chemie (ZHB) PubChem (16236084) PubChem (22770842) PubChem (24051735) PubChem (104847) PubChem (134602) PubChem (107645) PubChem (5284645) PubChem (5284657) PubChem (5933650) PubChem (6427035) PubChem (6437352) PubChem (6915834) PubChem (102258135) PubChem (7592428) PubChem (7592429) PubChem (7592432) PubChem (7592435) PubChem (13932155) PubChem (125136540) PubChem (131665000) PubChem (133687345) | |||
| 3 | F, G, H (A, B, C) | water | water | 18.0 | 384 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 264 (UniProt: Q8NKB0)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Ser 102 | engineered mutation |
| His 153 | Val 153 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86404.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 640.8 | |
| All* | Total formula weight | 87045.7 |
